That has led researchers to genetically alter pigs in an attempt to make their organs a better match. The biotech company that bred the pig for the Penn study, eGenesis of Cambridge, Massaschetts, is aiming to do that with gene editing. Scientists at the company used Crispr to make a total of 69 genetic edits … Read more
The purpose of the current trial is to assess the gel’s safety and longevity, not how well it prevents pregnancy. Participants were asked to use a back-up form of birth control while being enrolled in the trial. The gel is designed to dissolve at the end of its lifetime, so the men will be followed … Read more
For Gastón Paladini, pork is a family affair. In 1923, his great-grandfather Don Juan Paladini moved from Italy to Santa Fe, Argentina, where he started putting a South American twist on classic Italian sausage recipes. Eventually, Don Juan’s company became one of Argentina’s largest meat producers. It still bears the family name: Paladini. But in … Read more
It’s been hard recently to think about anything other than the wars and humanitarian crises raging around the world. Climate change has left its mark in what was almost certainly the hottest year in human history—there were unprecedented heat waves, intensified forest fires, torrential rain, and floods like those in Libya that caused devastation after … Read more
In September, Elon Musk’s brain-implant company Neuralink announced the much-anticipated news that it would start recruiting volunteers for a clinical trial to test its device. Known as a brain-computer interface, or BCI, it collects electrical activity from neurons and interprets those signals into commands to control an external device. While Musk has said he ultimately … Read more
So far, only nine centers across the US are currently offering Casgevy, which may limit who gets access to it. Vertex says the number of participating sites will grow in the coming weeks and months. And despite the promise of a pain-free future, the grueling process of getting Casgevy may be a deterrent for some. … Read more
Our B cells help prevent us from getting sick. Their job is to make antibodies, immune system proteins that fight off viruses and other foreign invaders. And they make a lot of antibodies—thousands of them every second. What if these antibody factories could be harnessed to make other things the body needs? That’s the idea … Read more
Digital health company Celero Systems is developing an electronic pill that can measure heart rate, breathing rate, and core temperature—from inside the human stomach. As a first step, the company envisions people with ongoing conditions using the digital capsule to monitor their vital signs at home. But in the future, they hope to use it … Read more
Casgevy uses the Nobel Prize–winning technology Crispr to modify patients’ cells so that they produce healthy hemoglobin instead. The Crispr system has two parts: a protein that cuts genetic material and a guide molecule that tells it where in the genome to make the cut. To do this, a patient’s stem cells are taken out … Read more
Scientists use harmless viruses to ferry and insert the new genetic material because of their natural ability to get inside cells. But the potential for these viruses to accidentally trigger another cancer has long been considered a theoretical risk. In its notice, the FDA said the use of these viruses may have played a role … Read more