How Many Microbes Does It Take to Make You Sick?

The original version of this story appeared in Quanta Magazine. For a pathogen to make us sick, it must overcome a lot. First it has to enter the body, bypassing natural barriers such as skin, mucus, cilia, and stomach acid. Then it needs to reproduce; some bacteria and parasites can do this virtually anywhere in … Read more

Bird Flu Reaches the Antarctic for the First Time

This story originally appeared in The Guardian and is part of the Climate Desk collaboration. Avian flu has reached the Antarctic, raising concerns for isolated populations of penguins and seals that have never been exposed to the deadly H5N1 virus before. The full impact of the virus’s arrival is not yet known, but scientists are … Read more

History Says the 1918 Flu Killed the Young and Healthy. These Bones Say Otherwise

In the last hard days of World War I, just two weeks before world powers agreed to an armistice, a doctor wrote a letter to a friend. The doctor was stationed at the US Army’s Camp Devens west of Boston, a base packed with 45,000 soldiers preparing to ship out for the battlefields of France. … Read more

In Defense of the Rat

Suddenly, Franks realized she had another meeting to get to, and here she was in a room full of free-ranging rats. She couldn’t just open the door and leave—rats would surely escape. But catching each rat and putting it back into the hutch would take forever. “I think, you know, we should probably get them … Read more

Why It’s Too Soon to Call It Covid Season

But the degree to which people accept the new shots might control whether and when a winter surge arrives. “We know from this virus, year over year, people’s immune response to each vaccine or boost starts waning at that six- to eight-month time point,” says Mark Cameron, an associate professor of population and quantitative health … Read more

Inside the Race to Stop a Deadly Viral Outbreak in India

On the morning of September 11, critical care specialist Anoop Kumar was presented with an unusual situation. Four members of the same family had been admitted to his hospital—Aster MIMS in Kozhikode, Kerala—the previous day, all similarly sick. Would he take a look? He gathered his team of doctors to investigate. Soon they were at … Read more