At the end of 2023, we witnessed an important moment in the history of medicine: For the first time, the US Food and Drug Administration approved a therapy that uses Crispr gene editing. This new therapy was developed by Crispr Therapeutics and Vertex Pharmaceuticals to treat sickle cell disease, an ailment caused by a single-letter … Read more
Timothée Chalamet said ‘Wonka’ is different from Gene Wilder & Johnny Depp’s version of the Roald Dahl character Timothée Chalamet recently claimed that Wonka is entirely different from Johnny Depp and Gene Wilder’s versions. The 27-year-old actor and his co-star Hugh Grant told Entertainment Tonight in an exclusive interview how “crazy” it feels to reenact such … Read more
The cinematic history of Willy Wonka is rich and layered, and Timothée Chalamet is excited to be adding to the pop-cultural tapestry of the iconic, magical chocolatier in Wonka. Chalamet and co-star Hugh Grant sat down with ET’s Cassie DiLaura during a press day in London on Wednesday, and the 27-year-old star opened up about “crazy” … Read more
New research seems to show the potential of a CRISPR-based gene therapy meant to neuter certain forms of cardiovascular disease. In the world’s first human trial of the therapy, people given the highest doses experienced significant and long-lasting reductions in their low-density lipoprotein cholesterol (LDL-C). The treatment could be used to help people genetically predisposed … Read more
While the Novartis trial was happening, Lustig and others were working on ways to restore hearing in genetic forms of hearing loss. In 2019, Lustig and his collaborators showed that OTOF gene therapy could be used to restore hearing in mice lacking the otoferlin protein. A separate group in Germany published similar findings in 2021, … Read more
KISS legends Gene Simmons and Paul Stanley are being dragged to court over the COVID death of one of their longtime guitar techs … and his family say it all started with Paul. According to a new lawsuit, obtained by TMZ, the family of late KISS guitar tech Francis Stueber says he died a couple … Read more
Best known for his comedic roles, as well as frequent collaborations with other comedy legends like Richard Pryor and Mel Brooks, Gene Wilder seems like one of those rare actors who just about everyone likes. He brought a certain endearing quality to the roles he played, even if his characters were morally questionable or flawed. … Read more